NAIT is characterised by the destruction of platelets in the fetus or newborn in response to certain platelet antigens (surface proteins) that the fetus has inherited paternally but are not present in the mother. Platelets are the smallest type of cells that circulate in the bloodstream and are important in preventing and stopping bleeding.
The mother sees these antigens as “foreign” and may respond by producing antibodies against these intruders. Antibodies, an important part of the body’s immune system, may cross the placenta, enter the baby’s bloodstream and destroy her unborn baby’s platelets. Spontaneous bleeding into the brain ICH (intracranial hemorrhage) or other major organs may occur putting the baby at serious risk of death or permanent brain damage causing lifelong disabilities.
Occurring in approximately 1:1000 pregnancies NAIT is the most common cause of severely low platelets in an otherwise healthy neonate and is often undiagnosed or misdiagnosed. Signs apparent at birth may include petechiae which is bruising that appears when blood vessels (capillaries) rupture and leak into the skin. The blood test that parents undergo to ascertain if they have a platelet antigen mismatch is called HPA genotyping.
For further information please email firstname.lastname@example.org
Parents if you have been diagnosed with, or suspect that you may have Neonatal Alloimmune Thrombocytopena and would like to join our private support group please email us here If you are on Facebook you can send us a private message via our public facebook page here and our admin team will get back to you.
Supporting #MediaplanetUK and this years Genetic Disorders Campaign!
In 2015 we partnered with Mediaplanet UK on the 2015 Genetic Disorders Ca…
Marianne’s walking the English South West coastal path!!
Coming up to her son Toby’s first birthday and to mark the horrendo…
Kelly and her team climb the South Wales 3 peaks!!
A huge thank you to Kelly Marshall-Stradling and her team who walked the South W…
Nait bear visits NYC, and spends time with Ethan Jones in Hampshire, England
Nait bear has been part of the NAIT family for a long time so it only seemed rig…
Nait bear visits with the Lindell family for Christmas in North Dakota USA!
Lana Lindell’s family with sons Rhett 6 and Bennett 2 are visited by Nait…
Nait Bear visits New Plymouth, Taranaki, New Zealand home of 3 special little gi…
Hello from the Naki! We were so pleased to host Nait bear, he slept with Amelia…
Photo update!! NB’s 5th Nuts Challenge Sat September 3rd 2016
Once again we have an intrepid team taking part in this year’s Nut’s…
NAIT mum Hope George hosts April Matilda Jane Clothing fundraiser
NAIT mum Hope George from Whitehouse, Texas, USA is a Trunk Keeper for Ma…
2016 NAIT Awareness week 25 – 31 March!!!
To kick off NAIT awareness week, Naitbabies have a competition for you…
Research and treatment protocols are ongoing.
Always consult a qualified medical specialist in this field. Cases of neonatal alloimmune thrombocytopenia should be managed in specialised Fetal Medicine Units.
We are not medical doctors. All references and materials are for educational and information purposes only.