This is a blood related disease that can affect the fetus or newborn due to human platelet antigen incompatibility. Platelets are a type of blood cell involved in blood clotting. This may cause the mother to produce antibodies in response to certain antigens, structures that can be recognised as foreign, that the baby has and the mother doesn’t. The antibodies attack the antigens, destroying platelets in the baby who is then at risk of spontaneous bleeding into the brain (ICH), stomach or spinal chord and can be at serious risk of brain damage or death.
NAIT is analogous to HDFN – Hemolytic disease of the fetus and newborn – a red blood cell disease.
Please note that we are not medical doctors. All references and materials are for educational and information purposes only. Research and treatment protocols are ongoing.
Always consult a qualified medical specialist in this field. Cases of neonatal alloimmune thrombocytopenia should be managed in Fetal Medicine Units.
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