Naitbabies are a non-profit organisation started in 2011 to provide support to parents and families and raise public knowledge of a rare and serious genetic disorder of the blood most people have never heard of “Neonatal Alloimmune Thrombocytopenia”  known as NAIT or FNAIT.

NAIT is characterised by the destruction of platelets in the fetus or newborn in response to certain platelet antigens (surface proteins) that the fetus has inherited paternally but are not present in the mother. Platelets are the smallest type of cells that circulate in the bloodstream and are important in preventing and stopping bleeding.

The mother sees these antigens as “foreign” and may respond by producing antibodies against these intruders. Antibodies, an important part of the body’s immune system, may cross the placenta, enter the baby’s bloodstream and destroy her unborn baby’s platelets. Spontaneous bleeding into the brain ICH (intracranial hemorrhage) or other major organs may occur putting the baby at serious risk of death or permanent brain damage causing lifelong disabilities.

Occurring in approximately 1:1000 pregnancies NAIT is the most common cause of severely low platelets in an otherwise healthy neonate and is often undiagnosed or misdiagnosed. Signs apparent at birth may include petechiae which is bruising that appears when blood vessels (capillaries) rupture and leak into the skin. The blood test that parents undergo to ascertain if they have a platelet antigen mismatch is called HPA genotyping.

NAIT is seen as the platelet equivalent of the red blood cell disease HDFN – Hemolytic Disease of the Fetus and Newborn more commonly known as Rhesus disease.  Routine antenatal care has included screening of all expectant mothers for HDFN since the early 1970’s. No country carries out antenatal screening for NAIT although it has been known about since the 1950’s and is very well documented.  Rarer diseases are screened for. Treatment is available for mothers who have developed antibodies against their unborn baby’s platelets and the success rate is high. If subsequent pregnancies are not treated they may also be at risk. Screening for NAIT should be standard and routine! 


For further information please email

Parents if you have been diagnosed with, or suspect that you may have Neonatal Alloimmune Thrombocytopena and would like to join our private support group please email us here  If you are on Facebook you can send us a private message via our public facebook page here and our admin team will get back to you.




Naitbabies is a Member of

Rare Disease UK

Australian NAIT Registry

Australian NAIT Registry



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Research and treatment protocols are ongoing.

Always consult a qualified medical specialist in this field. Cases of neonatal alloimmune thrombocytopenia should be managed in specialised Fetal Medicine Units.

We are not medical doctors. All references and materials are for educational and information purposes only.