Title: The maternal immune response to fetal platelet GPIbα causes frequent miscarriage in mice that can be prevented by intravenous IgG and anti-FcRn therapies
Conglei Li,1,2 Siavash Piran,1,2 Pingguo Chen,2,3 Sean Lang,1,2,3 Alessandro Zarpellon,4 Joseph W. Jin,2,3 Guangheng Zhu,2 Adili Reheman,2 Dianne E. van der Wal,2 Elisa K. Simpson,1,2 Ran Ni,5 Peter L. Gross,5 Jerry Ware,6 Zaverio M. Ruggeri,4 John Freedman,1,2,7 and Heyu Ni1,2,3,7,8
1Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada. 2Toronto Platelet Immunobiology Group and Department of Laboratory Medicine, Keenan Research Centre in the Li Ka Shing Knowledge Institute of St. Michael’s Hospital, Toronto, Ontario, Canada. 3Canadian Blood Services, Toronto, Ontario, Canada. 4Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, California, USA. 5Department of Medicine, McMaster University, Hamilton, Ontario, Canada. 6Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA. 7Department of Medicine and 8Department of Physiology, University of Toronto, Ontario, Canada.
Address correspondence to: Heyu Ni, Canadian Blood Services and Department of Laboratory Medicine and Pathobiology, St. Michael’s Hospital, University of Toronto, Room 420, LKSKI — Keenan Research Center, 209 Victoria Street, Toronto, Ontario, Canada M5B 1W8. Phone: ; Fax: 416.864.5826; E-mail: ac.hms@hin.
Title: Platelet antibodies and fetal growth: maternal antibodies against fetal platelet antigen 1a are strongly associated with reduced birthweight in boys.
Author information: Tiller H1, Killie MK, Husebekk A, Skogen B, Ni H, Kjeldsen-Kragh J, Øian P.
1Laboratory Medicine, Department of Obstetrics and Gynecology, University Hospital of North Norway, Tromsø, Norway.
Post Transfusion Purpura – PTP
Author: Edwin Massey
Clinical Guidelines and Policies from NHSBT, UK
INFORMATION INF153/1.1 Effective: 13/06/11
Title: New K103 β3 allele identified in a context of severe neonatal thrombocytopenia.
Authors: Jallu V, Bianchi F, Bertrand G, Kaplan C.
Platelet Immunology Laboratory, INTS, Paris, France.
Title: Role of kleihauer test in detection of fetomaternal haemorrhage (FMH) in women with reduced fetal movements
Authors: S Iftikhar, S Attarbashi, R El Gawly
Royal Elbert Edward Hospital, Wigan, UK
Title: Fetomaternal haemorrhage – an observational study
Authors: S Campbell, M O’Riordan
Cork University Maternity Hospital, Cork, Ireland
Title: Placental immunology and maternal alloimmune responses
Authors: Amanda Symington 1, Bosco Paes 2
1 Hamilton Health Sciences, McMaster Children’s Hospital (Neonatal Division), McMaster University, Hamilton, Ontario, Canada
2 Department of Pediatrics (Division of Neonatology), McMaster University, Hamilton, Ontario, Canada
Title: Fetal and neonatal alloimmune thrombocytopenia: prenatal interventions
Authors: Marije M. Kamphuis and Dick Oepkes
Department of Obstetrics, Leiden University Medical Centre, Leiden, The Netherlands
Title: A review of pathophysiology and current treatment for neonatal alloimmune thrombocytopenia (NAIT) and introducing the Australian NAIT registry
Authors: Zoe K. MCQUILTEN,1,2 Erica M. WOOD,3,4 Helen SAVOIA 5 and Stephen COLE 6
1 Clinical fellow, Transfusion Medicine Services, Australian Red Cross Blood Service,
2 Department of Epidemiology and Preventive Medicine, Monash University,
3 Transfusion Medicine Specialist, Transfusion Medicine Services, Australian Red Cross Blood Service,
4 Department of Clinical Haematology, Faculty of Medicine, Nursing and Health Sciences, Monash University,
5 Consultant Haematologist, Department of Haematology, Royal Women’s Hospital, and 6 Maternal-Fetal Medicine Specialist, Royal Women’s Hospital, Melbourne, Australia.
Title: Noninvasive fetal genotyping of human platelet antigen-1a
Authors: PG Scheffer,a,b A Ait Soussan,a OJHM Verhagen,a GCML Page-Christiaens,b D Oepkes,c M de Haas,a CE van der Schoota
a Department of Experimental Immunohaematology, Sanquin Research Amsterdam and Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands
b Division of Perinatology and Gynaecology, University Medical Centre Utrecht, Utrecht, the Netherlands
c Department of Obstetrics, Leiden University Medical Centre, Leiden, the Netherlands
Correspondence: Dr CE van der Schoot, Sanquin Research Amsterdam, PO Box 9190, 1006 AD Amsterdam, the Netherlands. Email e.vanderschoot@sanquin.nl
Title: Thrombocytopenia in neonates and the risk of intraventricular hemorrhage: a retrospective cohort study.
Authors: Jeannette S von Lindern 1,2*†, Tjitske van den Bruele1,2†, Enrico Lopriore1 and Frans J Walther1
1 Division of Neonatology J6-S, Department of Pediatrics, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands.
2 Department of Pediatrics, Groene Hart Hospital, Gouda, The Netherlands.
Title: Fetal and Neonatal Alloimmune Thrombocytopenia A Management Algorithm Based on Risk Stratification
Authors: Luis D. Pacheco, MD, Richard L. Berkowitz, MD, Kenneth J. Moise, Jr, MD, James B. Bussel, MD, Janice G. McFarland, MD, and George R. Saade, MD
Division of Maternal Fetal Medicine, Department of Obstetrics & Gynecology, The University of Texas Medical Branch at Galveston, Galveston, TX 77555-0587, USA. ldpachec@utmb.edu
Title: The incidence and outcomes of fetomaternal alloimmune thrombocytopenia: A UK national study using three data sources.
Authors: Knight M, Pierce M, Allen D, Kurinczuk JJ, Spark P, Roberts DJ, Murphy MF.
National Perinatal Epidemiology Unit, University of Oxford, Oxford. NHS Blood and Transplant Nuffield Department of Clinical Laboratory Sciences, John Radcliffe Hospital, University of Oxford, Oxford, UK.
Title: The cellular immunobiology associated with fetal and neonatal alloimmune thrombocytopenia
Authors: Stuge TB, Skogen B, Ahlen MT, Husebekk A, Urbaniek SJ, Bessos H.
Laboratory Medicine, University Hospital of North Norway, Tromsø, Norway. tor.brynjar.stuge@uit.no
Title: Low-avidity anti-HPA-1a alloantibodies are capable of antigen-positive platelet destruction in the NOD/SCID mouse model of alloimmune thrombocytopenia.
Bakchoul T1, Kubiak S, Krautwurst A, Roderfeld M, Siebert HC, Bein G, Sachs UJ, Santoso S.
1Institute for Clinical Immunology and Transfusion Medicine, Medical Faculty, Justus Liebig University Giessen, Giessen, Germany.
